Pharmaceutical blister packaging machine|The importance of tightness of pharmaceutical packaging

Pharmaceutical blister packaging machine

The tightness of pharmaceutical packaging materials is an important physical monitoring index related to the quality of pharmaceuticals. There is no room for sloppy packaging in the process of drug packaging. In order to better ensure the safety of drug packaging, drug packaging companies should not only be ingenious in packaging design, but also strictly control the production process. Among them, drug packaging testing is one of the key links. In order to To better ensure the quality of drugs, it is necessary for drug packaging companies to test the tightness of drug packaging.
The so-called tightness refers to the characteristics of the packaging bag to prevent the entry of other substances or the escape of the contents. In the production process of pharmaceutical packaging bags, because there are many production links, there may be leakage of heat sealing, pressing through, or cracks and micropores in the material itself, resulting in small holes or weak points of strength that are connected inside and outside.
Therefore, if the sealing performance is not up to standard, the external water vapor will enter the medicine packaging material and contact the internal medicine, and the medicine will be damp, invalid or even deteriorated, which will endanger the health of the patient. Therefore, the drug should be packaged in a well-sealed package during the entire validity period, and the drug packaging material must undergo professional and strict sealing performance testing.
There are many drugs that the pharmaceutical industry needs to test the tightness of the packaging, and the three common ones are as follows:
1. Airtight containers: vials, ampoules, syringes, oral liquids, sterile bags, infusion bags/bottles, water injections, powder injections, BFS bottles, API bottles, BPC bottles, FFS bottles and other airtight containers.
2. Blister packaging: powders, tablets, capsules, contact lenses and other samples in the form of blister packaging.
3. Small headspace packaging: granule packaging, small dose powder and other packaging with very small headspace.
The overall sealing performance and internal gas residues of pharmaceutical vacuum packaging directly affect the quality of pharmaceuticals, and are indicators that relevant companies must pay attention to and control.